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Erectile dysfunction and CHD
Years ago, Viagra made the unexpected transition from hypertension and angina drug contender to erectile-dysfunction blockbuster, only to journey back as a treatment for PAH. Recent years have seen a flurry of studies suggesting that erectile dysfunction and coronary disease are closer cousins than ever expected.
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Showing 1 - 16 of 16 documents.
Brain/Kidney/Peripheral
ED in diabetic men linked to CVD, CHD, and stroke
1 COMMENT - Nov 26, 2010 10:30 EST
Results from a new analysis of the ADVANCE trial shows that baseline ED is associated with a 19% higher risk of cardiovascular disease events, a 35% increased risk of coronary heart disease, and a 36% increased risk of cerebrovascular disease.
Prevention
Depression and erectile dysfunction are independent risk factors for heart disease
14 COMMENTS - Jul 16, 2010 15:00 EDT
The presence of depressive symptoms increased the risk of cardiovascular events in men with erectile dysfunction, a new study shows.
Medscape Medical News
Men with prostate cancer at higher risk of thromboembolic disease
Apr 15, 2010 14:15 EDT
The greatest risk was for deep vein thrombosis in men with prostate cancer on endocrine therapy, whose risk was more than doubled. Teasing out the risk associated with the disease process, choice of therapy, and other patient factors requires further study.
Medscape Medical News
Erectile dysfunction a red flag for mortality, cardiovascular events
1 COMMENT - Mar 17, 2010 13:45 EDT
New findings suggest erectile dysfunction is a marker for increased risk of death and heart attacks in men with heart disease.
Prevention
ED predicts future CVD but doesn't add beyond traditional risk factors
1 COMMENT - Jan 19, 2010 17:00 EST
After adjustment for conventional risk factors, men with ED are at a 40% greater risk of developing cardiovascular disease than men without ED. Still, the addition of ED did not improve the prediction of cardiovascular-disease incidence in men beyond that of conventional risk factors.
Interventional/Surgery
Next up: Drug-eluting stents for erectile dysfunction
8 COMMENTS - Oct 2, 2009 17:45 EDT
In what may be the first clinical trial to test a DES in the pudendal artery, investigators at nine sites are looking at whether pudendal stenting is safe and effective in men who have failed PDE-5 inhibitors.
Hypertension
"Natural" ED product recalled; contains PDE-5 inhibitor
Jun 22, 2009 16:00 EDT
People taking the nonprescription dietary supplement marketed under the name Stamina-Rx "should stop using it immediately," the FDA is warning consumers.
Prevention
Erectile dysfunction in 40-something men signals high risk of later CV disease
Feb 6, 2009 10:45 EST
A community-based study finds ED to be a cardiovascular risk marker in what may be the youngest and broadest population yet. (Inman BA et al. Mayo Clin Proc 2009; 84:108-113.)
Lipid/Metabolic
Confirmation that erectile dysfunction increases risk of CVD among diabetics
May 22, 2008 17:00 EDT
Two new trials confirm that erectile dysfunction should be treated as a powerful early-warning sign for MI and other serious cardiovascular events in patients with diabetes. And one of the studies finds that statins and PDE-5 inhibitors might reduce such events. (Gazzaruso C et al. Ma RCW et al. J Am Coll Cardiol 2008; 51:2040-2044, 2045-2050.)
News
Sexual dysfunction common in women with hypertension
May 19, 2006 12:00 EDT
Researchers find that sexual dysfunction is common among women with hypertension, with a prevalence roughly twice that of normotensive women. They assert that more information on the recognition and management of sexual dysfunction among women with hypertension should be a research priority. (American Society of Hypertension 21st Annual Scientific Meeting and Exposition.)
News
Adding atorvastatin to sildenafil nonresponders helps improve erectile dysfunction
Feb 23, 2006 16:15 EST
Researchers say the results from this small pilot study suggest that improving vascular endothelial dysfunction can help improve erectile problems in men who do not initially respond to treatment. (Herrmann HC et al. J Sex Med 2006; 3:303-308.)
News
Strongest proof yet that ED is "red flag" for CHD
4 COMMENTS - Jan 23, 2006 16:00 EST
Erectile dysfunction is extremely common and could prove to be one of the strongest risk factors to date identified for coronary heart disease, new studies show. Hence, a careful sexual history may provide important clinical information beyond the detection of ED, the researchers conclude. (Min JK et al. Saigal CS et al. Grover SA et al. Arch Intern Med 2006; 166:201-206, 207-212, 213-219.)
News
More proof: Erectile dysfunction a harbinger of CVD
Dec 20, 2005 16:00 EST
A new, prospective study adds heft to the erectile-dysfunction hypothesis, indicating that men with erectile dysfunction and no cardiovascular disease have a 45% chance of having a cardiovascular event within five years. (Thompson IM et al. JAMA 2005; 294:2996-3002.)
News
Viagra: First demonstration of an effect on human heart
Oct 25, 2005 14:00 EDT
Scientists from Johns Hopkins have shown for the first time that sildenafil appears to have a beta-blocker-like effect on the human heart. This indicates that the drug, and others in the same class, may be potential heart-failure therapies, they say. (Borlaug B et al. Circulation 2005; 112: 2642-49.)
News
More evidence that erectile dysfunction is early sign of CHD
Oct 12, 2005 10:30 EDT
A new study has shown that patients with erectile dysfunction have higher levels of CRP, more frequent coronary artery calcifications, and more impaired endothelial function of the brachial artery than men without this condition, providing further weight to the idea that erectile dysfunction represents an early clinical manifestation of coronary artery disease. (Chiurlia E et al. J Am Coll Cardiol 2005; 46:1503-1506.)
News
Erectile dysfunction: A marker for silent CAD in diabetics?
Jun 22, 2004 16:00 EDT
Diabetic patients don't always inform doctors about erectile dysfunction. Yet this may be a clue to silent coronary disease, Italian researchers say. (Gazzaruso C et al. Circulation 2004.)

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