Clotblog with Dr Samuel Goldhaber

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Aspirin for stroke prevention in AF: More risk than benefit?

Nov 4, 2011 15:50 EDT


On the heels of a large Danish cohort study that indicated that aspirin had little effect in stroke prevention for patients with atrial fibrillation and with the rise of promising novel anticoagulants, what role is there for aspirin as an agent to prevent stroke?

See also:

Aspirin should not be used for stroke prevention in AF patients

Olesen JB, Lip GYH, Lindardsen J, et al. Risks of thromboembolism and bleeding with thromboprophylaxis in patients with atrial fibrillation: A net clinical benefit analysis using a 'real world' nationwide cohort study. Thromb Haemost 2011; 106:739-749. Abstract.








Your comments
Aspirin for stroke prevention in AF: More risk than benefit?
# 1 of 1
November 11, 2011 09:43 (EST)
Ed Petrus
Low dose aspirin is safe and effective.  If one has GI complications, use a low-dose aspirin that dissolves and is absorbed in your mouth, such as Fasprinm which gets into the blood stream in 5 minutes.

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Who's Talking
Samuel Z Goldhaber, MD
Professor of Medicine
Harvard Medical School
Director, Venous Thromboembolism Research Group
Co-Director, Anticoagulation Management Service
Cardiovascular Division
Brigham and Women's Hospital
Boston, MA