Clotblog with Dr Samuel Goldhaber
View all posts »Nonhemorrhagic adverse effects of warfarin
Jun 22, 2012 07:35 EDT-
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The nonhemorrhagic side effects of warfarin—including alopecia, osteoporosis, coronary artery calcification, a feeling of being cold, and fatigue—are certainly less serious than hemorrhagic side effects (such as major GI bleeding) but it's nonetheless important to monitor them.
Have your patients experienced other nonhemorrhagic side effects of warfarin?
See:
Weijs B, Blaauw Y, Rennenberg RJMW, et al. Patients using vitamin K antagonists show increased levels of coronary calcification: An observational study in low-risk atrial fibrillation patients. Eur Heart J 2011; 32:2555-2562. Abstract.
Caraballo PJ, Heit JA, Atkinson EJ, et al. Long-term use of oral anticoagulants and the risk of fracture. Arch Intern Med 1999; 159:1750-1756. Abstract.
Budnitz DS, Lovegrove MC, Shehab N, et al. Emergency hospitalizations for adverse drug events in older Americans. N Engl J Med 2011; 365:2002-2012. Abstract.
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