Heartfelt with Dr Melissa Walton-Shirley

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Geoffrey Hartzler-my hand is over my heart in hommage to your work. Thank you! Thank you!!! Thank You!!!!!

Oct 15, 2008 15:18 EDT


Entertaining and informative, this witty look back at the early genius and ridiculously rudimentary pci techniques made me feel as if the first ptca's were done in an era when we were still rubbing two sticks together to start a fire.  I fully expected to leave this presentation only to see  Rachael Welch running from a dinosaur in her bear skin two- piece.

I gained a whole new respect for intervention today but still marveled at How on earth  we ever got here from the dark but genius age of Gruentzig and colleagues?  Let me just navigate you through the typical day in the cath lab" way back when"as described by  Geoffrey Hartzler as told with Jackie Gleason style humor. 

A typical PTA case:  (That's Peripheral transluminal angioplasty,  for you babes born long after the first procedure was performed)

The year is 1980 BC, ....I mean AD.  You were handed an .063 guide wire. ( No, you weren't going to fence with it you were going to navigate a trek from  the femoral artery to the aorta with it.)   Too bad we didn't recycle back then,  After  the cath, one could have used it to do a nice artsy wire sculpture. Once the coronaries were visualized,  you requested the "steam kettle".  No joke,  a "steam kettle" to help warm the guide and sculpt it into the shape  needed.  After it was determined that the patient was to have a PTA, you took a stiff tipped balloon with a distal spring wire , (kind of reminded me of the size and shape of a tonsil tipped suction apparatus) and reamed the heck out of the vessel.  There was only one balloon, the advantage of which was that you didn't have to waste all that time sizing, etc.) When you did your 5-6 atm.  inflations, "the balloon always , ALWAYS  broke".  There was NO HEMOSTATIC valve which meant you had soggy sox and shoes, dripping with the patient's blood through out the entire  procedure. 2 unit transfusions were not uncommon at the close of a routine procedure. 

No time was wasted on  a Pharmacology decision making process  as the patient received isordil po, dextran, heparin and at the end of every case, they were reversed with protamine.  ASA and Dipyridamole were all they had back then in the way of oral angicoagulants, but they were FORBIDDEN because the surgeon refused to operate on the patient if they had taken an aspirin. 

Then, at the end of the day, everyone was so relieved and grateful to have an open vessel.   But really, what did they have to worry about?  After all, their procedural success rate was 72%!!! 

Dr. Hartzler then described his first successful PTA case for STEMI .  He asked for his case to be placed on the table to which the nurse replied that the cath had been canceled because he had developed chest pain with ST elevation and bradycardia.(That's about as ridiculous as saying I'm not going to dinner because I'm hungry).  He evaluated the ECG and sure enough, inferior injury pattern was full blown.  (This was July 1980).  Unfortuanately, the film was lost forever but he did show one that looked as if Charlie Chaplin would walk by, twirling his cane, at about 1 frame per second it seemed, that demonstrated the opening of an artery with  a GIGANTIC banana shaped  balloon.  The patient however became completely pain free and ST's were normal.  The LV gram normalized completely at a recath some weeks to months later.  By Joe, Dr. Hartzler, I do believe you were on to something!!

Thus PCI for STEMI was born.  And to think, we quibble today over such ridiculous things as surgical back up.  The way I look at it, if we aren't using a steam kettle to shape the guiding catheter, I think  the patient is probably pretty safe.   

Needless to say, I'll never view the  interventional world in the same light again.  In the now famous words of the infamous GARTH and Wayne of Wayne's world, every time I see Dr. Hartzler from now on.......I'm going to bow and say "We're not worthy, WE'RE NOT WORTHY!!"

 Because you know what.??.....we're not.  Nothing can compare with the story of the birth of PCI and the courageous and genius antics of the first cardiologists who invented PTA.  NOTHING.

 

 








Your comments
Geoffrey Hartzler-my hand is over my heart in hommage to your work. Thank you! Thank you!!! Thank You!!!!!
# 1 of 6
October 22, 2008 10:03 (EDT)
Christian JM Vrints

This story reminds me of a live case during a PTCA course that I attended as a young interventional cardiologist in Lausanne early in the eighties. The case went awfully wrong, live transmission was cut and we all believed that the patient was sent urgently to the cardiac surgeon. However, one hour later we were again connected to cathlab and Ulrig Sigwart told us that the patient was fine and was readied to bring her back to her room after the insertion of a new intracoronary device that fixed the ugly dissection flaps that were induced by balloon angioplasty. I do not recall if he already used the word stent but it was one of the first stents implanted in man.

Some years later I was invited to a meeting with Patrick Serruys in Eindhoven were he proposed to participate to the BENESTENT trial. I hesitated and did not participate to the study since at that time I believed that interventional cardiologists should not be sorcerer’s apprentices and should not put a stent in every lesion if you already had an excellent result after plain balloon angioplasty. It turned out that I was wrong.

Indeed we owe a lot to the founding fathers of interventional cardiology who showed us the direction and paved the way to point where are now.

 

Christian JM Vrints MD PhD FESC FACC

professor of Medicine and Cardiology
University of Antwerp

Belgium

# 2 of 6
October 22, 2008 06:37 (EDT)
Melissa

Christian,

Thanks so much for sharing your remembrances of the "early days" of pci.  A patient in our practice was the first in Kentucky to receive a stent. How curious a thing it was.  We didn't know quite what to expect.

 We owe a lot to those interventionalists  in our pci centers that continued to expand on the early experiences of the pioneers.  My mentor , the late Dr. Ron Masden, spent his life in a dark room, threading wires across impossible lesions.  He was often chastised for doing more than one vessel!! I know he would have been at the TCT meeting and would have especially loved to hear what is on the horizon with Xcience, Catania, etc. 

Appreciate your post.

Melissa

  

# 3 of 6
October 31, 2008 12:13 (EDT)
Saleem Seyal

Dear Melissa

For those of us who have been practicing the art and science of Interventional Cardiology for the past quarter of a century remember the early innovative days of PCI with awe and nostalgia. Emergence and progression of this new specialty has been chronicled by David Monagan and David O Williams, MD in the book, "Journey into the Heart" published by Gotham Books, 2007. I enjoyed reading about the pioneers in this field and their sometimes quirky and sometimes hauting but always interesting accounts of their personal and professional lives.  Starting with the chain-smoking, obscenities-spewing but lovable F. Mason Sones of the Cleveland Clinic where an accidental slippage of the catheter into the right coronoary artery  during an attempted aortic root injection gave birth to selective coronary arteriography. Charles Dotter of Oregon was an eccentric man who tinkered with wires and catheters and pioneered peripheral vascular dilatations with progressively increasing sizes of catheters-- "dottering". Melvin JUdkins of Oregon--a colleague of Dotter shaped catheters for selective injection of coronary arteries via the femoral approach. Coronary artery bypass was pioneered by Rene Favoloro in the 1960s. A workable heart lung machine was the result of hard work by C. WAlton Lillehei in Minnesota.

 Enter the swash-buckling and impressive, Andreas Gruentzig, an East German refugee with no formal training in cardiogy who quickly became the father of interventional cardiology. His rise in the medical circles was meteoric. Wooed by Spencer KIng and J.Willis Hurst, he was appointed at the prestigious Emory University and conducted his famous training courses there. GeofferyHartzler- the flash from kansas,  who performed the first PCI in an MI setting and showed extreme dexterity in reaching the far ends of coronories with his balloon catheter. He mesmerized his attendees at his courses. Introduction of some very cumbersome PCI procedures including, rotablation, atherectomy with their gradual exit from the stage is very intersting.  Stories of Swan-Ganz catheter, interventional electrophysiogy  and innovations in pacemakers and defibrillators are all extremely exciting. Stents have revolutionized the specialty and with their use, the specter of "acute closure'-- the dreaded complication of POBA,  has completely disappeared.

I worked with the late Ron Masden as well who, as you pointed out, was fearless and worked tirelessly in the interventional cardiology field. I was lucky to attend Gruentzig and Hartzler courses and am gratified at the maturation of a tremendously exciting specialty.

Regards Saleem

# 4 of 6
November 14, 2008 07:56 (EST)
Melissa

Saleem,

So sorry I missed your post.  I had to take a friend of our family  to Duke to try and get on an experiemental  chemo protocol and then the AHA, all the while trying to work in between. 

GREAT navigation through the history of PCI and other interventional developments.  I really enjoyed reading it and learned a lot too as I always do when we see each other!

I cannot tell you how much I miss Ron Masden.  For about 13 years, almost every Friday afternoon, he would call me with a run down of all the patients I'd referred to him.  During 2-3 Christmas Holidays, my secretary would come and get me out of a room and tell me there was someone there to see me.  When I would go to the front, there he would stand, gifts in both hands, fruit baskets, etc.  in his long wool  winter  coat. He had driven to clinic in Tompkinsville and then over the 40 miles to Glasgow.   It was odd to see him in the light of day without scrubs.  He was always suprisingly thinner and taller than I could remember because I rarely saw him without lead and scrubs. His gray hair always accentuated his pallor induced by a compete lack of sun exposure over the past 30 years.    He was smiling as I walked toward him, like he had a present for his mom, even though he was 20 years my senior and that last picture of him on that last holiday is in indelible postcard in my mind's eye. 

I am still hurt that he did not ever mention to me he was having difficulties of any type.  If only he had asked any of us, we could have probably steered him through it and away from trouble.  I think cardiologists should never treat themselves. I cannot tell you how many tears were shed on all of our behalf here as I'm sure there were in Louisville.  

Saleem, so glad to reminisce with you. Always appreciate your participation here on theheart.org. Hope to see you soon.

Melissa  

# 5 of 6
December 21, 2008 10:38 (EST)
M. Saleem Seyal, MD

Melissa

It is my turn to apologize for being tardy in checking your post. Thanks very much for your kind words. I have the utmost admiration and respect for you for your extremely exhaustive coverage of cardiology meetings and keeping us abreast of all the pertinent trial results. Your anecdotal and personal descriptions about the real patients are always welcome as well.

Ron masden was a wonderful senior colleague who was my mentor as well and I scrubbed with him on numerous occasions for interventional procedures on my own patients. I was completely unaware of his ailment as well. I did write an "In Memoriam" piece about him in Louisville Medicine and I was honored to have received a kind note from his widow afterward.

Keep up the good work!!  And may be one of these days, I might finally see you again in Glasgow, Ky. The last two times, we had not been able to connect.

Best Regards

Saleem

# 6 of 6
April 28, 2009 06:57 (EDT)
melissa

Saleem,

And I shall look forward to it as well! Thanks so much for your kind words and your post!

Melissa


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About Dr Melissa Walton-Shirley
Dr Walton-Shirley performs invasive cardiology, nuclear cardiology, and stress echocardiography in a private practice in Glasgow, KY.

Her chief medical interests are CHF/hypertrophic obstructive cardiomyopathy and the promotion of primary PCI for acute MI. Recently she played a significant role in helping to launch an ambitious pilot study of primary PCI in Kentucky, the Kentucky Primary Angioplasty Pilot Project. She has also participated in the TIMI 19, Duke-HF, NRMI, and CRUSADE trials and is proud to have been an advocate of the first smoke-free initiative in Kentucky (2011). She champions a smoke-free America.

Dr Walton-Shirley received her undergraduate degree at the University of Kentucky and went to medical school and did her residency and fellowship at the University of Louisville. She is married with two daughters. Her interests include singing, writing poetry and songs, fitness, and, of course, theheart.org.