Heartfelt with Dr Melissa Walton-Shirley

View all posts »

The E-cigarette: Should cardiologists add this to our bag of tricks?

Aug 25, 2012 09:00 EDT


When I opened my exam room door a couple of years ago, there he sat. The entire office staff, unbeknownst to me, were waiting and listening for my reaction. He smiled, holding his brand-new shiny electronic cigarette between his teeth, then tilted his head ever so slightly, keeping his eyes on mine as he slowly exhaled. He then removed it in a dramatic sweeping fashion, sort of like Thurston Howell III on my favorite Gilligan's Island episode in a smoking jacket with his wife Lovey at his side. A vapor wafted slowly from the end of the curious thing protruding from his mouth. "Well, what do you think?" he asked, chuckling. I replied, "I can tell you one thing. You are the first person in the history of my being a private-practice cardiologist to ever smoke anything while sitting on my exam-room table." Everyone laughed on both sides of the door, obviously with ears pressed. Until today's presentation by Dr Konstantinos Farsalinos, from Athens, Greece, I really didn't know what to think.

On that fateful day with my first interface ever with the device (other than an attempted sale by a hawker in an outlet in Orlando, FL a few years back), my patient quizzed me for more information. I told him we had no long-term data to attest to the safety of the "e-cigarette," and based on that fact, I really couldn't recommend it. Today's presentation made me soften toward it, although we don't have large randomized controlled trials or any long-term follow-up to back it. Even in this day and age, with our obsession with and addiction to "quality" data, some things are still just intuitive. As a testimony to the unknown long-term side effects, we banned "e-cigarettes" as well as all smoking in public venues in our hometown of Glasgow, KY around three years ago.

The presenters who preceded the e-cigarette study today gave an impressive review of information reaffirming that tobacco exposure at any dose can be lethal. An adolescent study revealed significant adverse effects on the vasculature of nine- to 20-year-old primary smokers with relatively little tobacco exposure, with only as much as a weekly indulgence. Another study mirrored the Helena MT US data that demonstrated that one in four STEMIs could be prevented by tobacco-smoking bans. But what about the e-cigarette? Should I as a practitioner recommend or allow it? Should I wait for my patient to bring it up, or should I recommend it as a first-line "treatment" for tobacco addiction?

The study today was disappointingly small, comparing cigarette smokers with "seasoned" e-cigarette smokers. It demonstrated no significant adverse effects on hemodynamics such as diastolic function by Doppler echo, heart rate, and systolic blood pressure compared with tobacco cigarettes. He noted that seasoned e-cigarette users smoke the device more than first-time users and thus did not want a novice population to taint the data. He is now analyzing data from 2-d speckle tracking and will add that information later to his studies.

I asked the presenter just about anything I could think of on the topic. Before I could get the question out of my mouth about the person in Florida who supposedly lost part of his tongue and a few teeth from an "explosion," he addressed it. The presenter offered that explosions are known to be a downside of lithium batteries, "not unique to the e-cigarette." "What about formaldehyde in the vapor and therefore cancer risk?" I asked. "You would have to smoke e-cigarettes for eight to 10 months in order to equal the exposure of one cigarette," he countered. "What about the fact that not all e-cigarettes are created equally?" I asked. "I have read that some contain nicotine, some don't. Others have flavorings, others don't. Should there be some regulation?" "Yes, I believe there should be regulation," he agreed. A journalist in the front of the room asked if he felt it might impact the number of house fires started by those who smoke in bed, and he answered "Yes, it would likely impact it, since it turns itself off after a few seconds of inactivity and heats up to less than 200º vs 800º as seen in tobacco cigarettes, in a matter of seconds." The sense was conveyed that feelings of repulsion and disgust we feel toward the habit of adults sucking a cigarette or a device to satisfy the basic behavioral and psychological yearnings seen in this addiction must be put aside. The sooner we accept it as an alternative, the better.

So, shall I add the electronic cigarette to my cardiologist's bag of tricks alongside varenicline (Chantix, Pfizer), bupropion, patches, gum, inhalers, and lozenges? Should I place it at the top or hide it in the very bottom, only bringing it out in a final act of desperation? Today's presentation suggests that the first step is to open up my bag of tricks and willingly dump in the e-cigarette, hinting I might now start to "allow it" and perhaps even bless it in the future as better than tobacco-smoke inhalation. After today, it certainly seems better and perhaps safer than tobacco, period. Now maybe I need to contact my patient and tell him he's welcome to "smoke" his e-cigarette on my exam-room table. On second thought, that might still be just a bit too much.

See also:

Electronic cigarettes don't adversely affect cardiac function

Smoking electronic cigarettes: A reasonable harm-reduction and smoking-cessation strategy?








Your comments
The E-cigarette: Should cardiologists add this to our bag of tricks?
# 1 of 18
August 25, 2012 03:34 (EDT)
Konstantinos Faarsalinos

Dear Colleague

Thank you very much for the comments you made on my study and for your presence to the conference. Perhaps i was not very clear during the press conference, so I hope i can clear some misunderstandings. Our study included tissue Doppler velocity measurements, and we have found no adverse effects on electronic cigarette users contrary to our findings in smokers. We are now in the process of  analyzing data from 2-dimensional speckle tracking echocardiography measurements that we have collected, and this will add information, since they are considered even more sensitive in detecting cardiac dysfunction.

Finally, i agree with you that the sample is small and that more studies are certainly needed. Our study sample is now 30 electronic cigarette users compared to 28 smokers, and the results are even more important from a statistical point of view. You will probably see a publication of our study in the near future. Until now, this is the biggest clinical study ever performed on electronic cigarettes, and the only one studying parameters of cardiac function.

 I would be honored if you could come to the presentation of the study tomorrow at 16:30 Munich time, in Athens-Village 3 room. You will see in full detail our results. Unfortunately the press office asked for only 5 slides to be presented during the press conference and we could not present the results in detail.

I would be happy to discuss with you in person all questions and thoughts you may have. Please feel free to contact me at any time.

 Thank you

Konstantinos Farsalinos, M.D.

# 2 of 18
August 25, 2012 04:43 (EDT)
Brewlady

The electronic cigarette was invented as a reduced-harm alternative to smoking tobacco.  The "dangers" that many anti-tobacco groups claim e-cigs MAY pose to users and bystanders simply don't exist.  Science has proven that inhaling burning tobacco is harmful.  Adult smokers who replace tobacco cigarettes with this device experience the same health benefits as someone who quits smoking.

Public Health officials who continue to discourage smokers from turning to products that are scientifically proven to be exponentially safer (e-cigs, Swedish snus, disolvables, etc.) are doing a huge disservice to public health.  Governments who include e-cigs in smoking bans, even though the vapor harms neither the user nor bystanders, are sending a message to smokers to keep smoking.  As more research is done, the results continue to confirm that these devices don't jeopardize bystanders.  Banning something that has already helped thousands of smokers become smoke-free is despicable. 

I smoked for 36 years and had given up on trying to quit.  Traditional methods like Chantix and the patch did not work.  Within a week of buying my first kit, not only was I not smoking, I had no desire to ever light up another cigarette.  That is something that no pharmaceutical product was able to do for me.  I have been tobacco-free for over two years, and I am disgusted and disappointed by anti-tobacco groups and government agencies that continue to ignore the reality of tobacco harm reduction.

As a former smoker, I encourage every smoker to do their own research, spend hours online reading both pro and con, and decide for themselves if it's worth trying.  I really didn't think it would work, but two years later, I can confidently say that it does work.  The anti groups may not care, the government may not care, but people like me in the vaping community do care. 
# 3 of 18
August 25, 2012 04:44 (EDT)
Gregory Conley
In regards to the study you may have read regarding the effects of electronic cigarettes on acute lung function, I highly recommend reading Dr. Michael Siegel's analysis -- http://tobaccoanalysis.blogspot.com/2012/01/new-study-shows-that-in-contrast-to.html I applaud you for keeping an open mind about these products. My two year anniversary of quitting smoking and switching to e-cigarettes passed by a week and a half ago. Personally, I would love to see a study done where researchers locate 30-50 long-term (2 years plus) e-cigarette users who were experiencing health problems before starting e-cigarettes and have access to medical reports that documented their lung function, blood pressure, etc. The research could compare those results to those measured after long-term e-cigarette usage. The logistics may be tough and the medical value less so than a tightly-controlled, multi-year clinical trial, but considering that the cat is out of the bag and millions of people worldwide are using e-cigarettes, the faster that research is published and distributed, the better. I am a director with the nonprofit, all-volunteer Consumer Advocates for Smoke-free Alternatives Association. I receive no compensation for my work and have never received compensation from any tobacco, e-cigarette, or pharmaceutical company.
# 4 of 18
August 25, 2012 06:30 (EDT)
Melissa Walton-Shirley

Dr. Farsalinos, I am honored you read my post and really enjoyed your presentation today. I have made the corrections and my apologies for  the error. I wish you the best of luck in your future studies on this and other topics!

Melissa

# 5 of 18
August 25, 2012 07:30 (EDT)
Konstantinos Farsalinos

Dr Shirley, i should congratulate you for the accurate and unbiased presentation. Thank you very much for your kind words and comments. Always staying at your disposal.

 

# 6 of 18
August 26, 2012 09:14 (EDT)
JEAN-PIERRE USDIN

Melissa

I recently traveled by airplane and as usual before taking off the video recommendations were given (we know them by heart!) however for the first time (to my knowledge) it was mentioned that E cigarettes are forbidden. I didn't ask for which reason. Does anybody know why? 

Probably PNC (“Personnel Navigant Commercial”) can easily answer to my request but I have no one under my thumb at this moment.

I am always like your blogs and your good sens of humour.   thank you for these relaxing moments

# 7 of 18
August 26, 2012 03:56 (EDT)
melissa

Thanks Jean Pierre! I wonder if it has something to do with the burden of trying to ascertain from a distance who is smoking and who isn't. Another thought is "What if everyone suddenly decided they wanted to use an e-cigarette?" How much vapor would there be?  Perhaps it's the lithium battery issue? Good question and so glad you enjoy HEARTFELT!!!

 

# 8 of 18
August 31, 2012 03:42 (EDT)
Thad Marney

Melissa, how much vapor would there be from a room full of people using e-cigarettes?  Most regular "vapers" intermittently use less than a teaspoon (5ml) of e-liquid per day as most devices produce between 3 and 10 watts.  Multiplied by 100 and it compares favorably with a typical theatrical fog machine that uses a quart or two of the same glycols and flavorants (sans the small percentage of nicotine) per hour running at well over 1000 Watts.  Also, keep in mind that even extremely high concentrations (well beyond what is possible for a roomful of vapers tooting away as fast as they can) of propylene glycol vapor is proven to be a powerful germicide and antibacterial with no known serious adverse effects--so few, in fact, that further research has been a low priority since the 1940's when tests were first conducted.  Research on smoke-free products' ability to reduce smoking is a bit of the cart pulling on the horse, instead I suggest that research be conducted on the potential for e-cigarettes to INCREASE the motivation to stop smoking and REDUCE the spread of airborne infectious disease.

I am a director with the nonprofit, all-volunteer Consumer Advocates for Smoke-free Alternatives Association. I receive no compensation for my work and have never received compensation from any tobacco, e-cigarette, or pharmaceutical company. 

# 9 of 18
September 1, 2012 06:43 (EDT)
msaleem M.D.

  

      i was hesitant to click on this email 'the trick if it could be played by cardiologist.'

 i am pleased to learn about this new development about a harmless, yet an effective      

way of quiting smoking. while warning my patients about smoking, i tell them,'we have   

treatment for every thing, except for smokoing.' now that e-cigarette has been devised, any attempts to oppose it at any level without a scientific reason, can be but from sick minds alone and need not be paid any heed to what so ever. but at the same time a long time follow up with an open mind, will be needed and should not be played down.

 

# 10 of 18
September 4, 2012 01:24 (EDT)
Margo S.

 New research (European Respiratory Society's Annual Congress in Vienna)  has shown that despite electronic cigarettes cause harm to the lungs. See: http://www.sciencedaily.com/releases/2012/09/120902113550.htm#.UEPPZldt6R0.facebook

# 11 of 18
September 7, 2012 07:40 (EDT)
Melanie

The problem with current research is that they are not fair representations. There have been no studies with a comparison of long term usage of e-cigarettes compared with long term smoking. My personal opinion is that e-cigarettes must be a better alternative to smoking. Cigarettes contain, as we know, over 5000 harmful chemicals. E-cigs contain just 5 ingredients (yes, one of them is nicotine, unless opting for a 0mg dosage). I'm not saying there are no risks to 'vaping', and I believe that e-cigarettes should not be used as a long term habit but ONLY as a short term solution to helping smokers quit the cigarettes. I too commend you on your balanced views of e-cig's amongst the apparent propaganda and health scares out there currently!

 Thad, your facts about the number of vapers in a room to produce a harmful amount of vapour in the air are very reassuring. I think this is something that could concern people, particularly non-smokers & non-vapers. Thanks for clearing that one up.

 For anybody interested, I stumbled across an interesting infographic here  - it outlines some interesting stats, all be it from an e-cig company so perhaps a little biased but i think the "5000 sunrises" line is very effective, really hits home.

Regards,

Melanie

# 12 of 18
September 10, 2012 10:54 (EDT)
Gary
I would not tell your patients or anyone else that they are "harmless" Less harmful? Possibly. Studies show the ecig to cigarette bad health ratio 10 to 1. I am a supplier of these and have been for over 2 years. After a 20 year smoking habit, this has changed my life. So much so I opened up shop because I wanted others to ecperience what I did. The self regulation of ecigs is the reason it has been able to grow so much. Thousands of Americans are new small business owners workign form their home and stores are opening up all the time. We need MORE suppliers and storefronts  though. As an experienced vapers of 3 years, I must say I feel just as good now as I did a month after I Quit smoking. I had a CT scan and EKG that checked out perfect recently. It does slightly raise blood pressure. It certainly does not stink or produce second hand smoke. I can drive in the car for two hours with the wondows rolled up and it doesn't bother my non smoking wife a single bit. The main chemicals in the liquid are FDA approved Vegetable Glycerine, and/or FDA approved Propylene glycol, ROHS's approved safe level Nicotine, and food grade flavorings. But the liquid is vaporized. it is not liek you are drinking the liquid. (not advisable) The immediate short term effects of this product (short term meaning 3 years, personally) are outstanding. Learn More at CASAA.org 

CASAA - THE CONSUMER ADVOCATES FOR SMOKE-FREE ALTERNATIVES ASSOCIATION

# 13 of 18
September 17, 2012 07:20 (EDT)
Graham

If you dig a little deeper you'll find the research you talk of was totally biased nonsense. As a matter of fact it was sponsored by Pfizer, the big phramaceutical company who not only sell the expensive and far more dangerous quit smoking drug Chantix (check the scarily common side effects) alongside many other quit smoking aids.

Unfortunately we're likely to see more BS propoganda against e-cigs from big tobacco and the pharmaceutical industry until they've found a way to regulate & profit from them themselves. (ie tax)

http://www.prweb.com/releases/eecigarettesafety/conflicts/prweb9899020.htm 

The conclusion is this, big phrama and tobacco companies are running scared, because with electronic cigarettes we really do have a product that genuinely DOES help smokers quit, and, when compared to regular cigarettes or drugs like Chantix, they are relatively harmless and have minimal side effects.  

Here's another example, just a few months ago the Lorillard tobacco company aquired Blu e-cigs, one of the most popular e-cigarette brands in the US.  

http://www.prweb.com/releases/2012/5/prweb9536334.htm 

 

# 14 of 18
October 14, 2012 10:14 (EDT)
joy
I actually started smoking analogs when I was 13. By the time I was 15 I was a pack and a half a day smoker. Finally, a month before my 45th birthday I started using the green smoke e-cigarette, that was 6 months ago, and I haven't had an analog since the first moment I recieved my Green Smoke. The e-cig is amazing! I, like many other addicted individuals tried everything over the years to quit to no avail untill the e-cig, now I breathe better, I sleep better, and I have alot more energy!! I feel alive again!! I wish that non smokers and the FDA would just stop putting something they don't understand down. My sister's doctor actually encouraged her to use her e-cigarette because it much improved her over all health and her high blood pressure is stableizing!! I will continue to use my e-cigarette and continue on with my improving health so the FDA and all the haters can just stay out of my business! Now that I use an e-cigarette, that's exactly what it is, MY BUSINESS, I'm not doing anything to effect the non smokers around me, not their health or my own so they should just leave me alone now.
# 15 of 18
October 19, 2012 12:17 (EDT)
E Cigarettes India

The electronic cigarette is 100% legal to smoke indoors, in pubs, clubs, night clubs, offices etc. Electronic cigarettes come with refillable cartridges which are available in a wide range of flavors and nicotine strengths. You can get menthol, regular, apple and strawberry flavored cartridges and they are available in light, full, medium and zero nicotine strengths.

# 16 of 18
November 14, 2012 03:56 (EST)
Rene
The elektrisk cigaret works like a charm and the best think with it is that you can smoke it almost everywere
# 17 of 18
December 16, 2012 05:20 (EST)
Nabil Kamas
They are safe and effective
I am not a smoker. However knowing the terrible complications of smoking I would seriously look at this alternative. Now, we have at least two year data on its efficacy and safety. That is more than what the FDA is requiring for approval of new drugs. Every piece of data there is on this product points out to its success. The only thing I see that stands in its way is the tobacco industry trying to bury it. They make trillions of dollars making smokers and their surrounding loved ones sick. I understand them not wanting products like this popular. I mean come on. Do we want to put these honest tobacco giants out of business?
Author's disclosure (Dec 16, 2012)
I have no relevant disclosures to make in connection with this topic.
# 18 of 18
March 13, 2013 03:56 (EDT)
JohnL Damico
electronic cigarette
Upon reflection the electronic cigarette is a healthier, cheaper and environmentally friendly alternative to smoking and as the awareness and the market grows they have great potential to successfully replace the harmful cigarettes we have all come to know and many of us have come to dread and fear.

Author's disclosure (Mar 13, 2013)
I have no relevant disclosures to make in connection with this topic.

You must be a member (with full membership) to post a comment.
Already a member?
Enter your login information below:
 Remember me on this computer
Enjoy all the benefits of theheart.org

With full membership, you can check out our educational and editorial content, search the site, receive our newsletters, join discussions, download slides and much more.

Membership is free!

About Dr Melissa Walton-Shirley
Dr Walton-Shirley performs invasive cardiology, nuclear cardiology, and stress echocardiography in a private practice in Glasgow, KY.

Her chief medical interests are CHF/hypertrophic obstructive cardiomyopathy and the promotion of primary PCI for acute MI. Recently she played a significant role in helping to launch an ambitious pilot study of primary PCI in Kentucky, the Kentucky Primary Angioplasty Pilot Project. She has also participated in the TIMI 19, Duke-HF, NRMI, and CRUSADE trials and is proud to have been an advocate of the first smoke-free initiative in Kentucky (2011). She champions a smoke-free America.

Dr Walton-Shirley received her undergraduate degree at the University of Kentucky and went to medical school and did her residency and fellowship at the University of Louisville. She is married with two daughters. Her interests include singing, writing poetry and songs, fitness, and, of course, theheart.org.