Private practice with Dr Seth Bilazarian

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Adopting ticagrelor (Brilinta): The pros and the cons

Jul 29, 2011 13:30 EDT


There are compelling reasons for immediately adopting Brilinta into your practice, but they stack up against equally convincing arguments for postponing its use.

How will you be adopting Brilinta?

See also:

Ticagrelor approval: US and Europe react

Ticagrelor approved at last for US market





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Your comments
Adopting ticagrelor (Brilinta): The pros and the cons
# 1 of 3
August 3, 2011 08:13 (EDT)
Scott

Dr Seth- I think the restrictive labeling that you mentioned as pro is not a really pro.  This product still have to be cognizant of bleeding, history of ICH or active pathological bleeding.  I don't see my center using it much because more with the side effects and cost along w/ stent thrombosis with Effient as my choice.  I have had good luck with this so far. 

Dr Scott
# 2 of 3
August 10, 2011 09:50 (EDT)
Melissa

Seth,

thank you so much for a really really excellent overview! As usual, concise and full of great information,......and practical as well!  Tempted to say" nothing short of Brilliant(a)!                   : )

Melissa

 
# 3 of 3
August 30, 2011 03:59 (EDT)
Piechota

In my opinion clopidogrel has well established benefit and risk profile and there is no obvious reason to switch to ticagrelor unless a patient has high on treatment (with clopidogrel) platelets activity. Testing for so called “clopidogrel resistance” can be easily, quickly and accurately performed with VeryfyNow system.

Piechota

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About Dr Seth Bilazarian
Seth Bilazarian MD has been a Clinical and Interventional Cardiologist at Pentucket Medical Associates in Massachusetts since 1993. He is board certified in Internal Medicine, Cardiovascular Medicine, Nuclear Cardiology, Vascular Ultrasound, Interventional Cardiology, and Vascular and Endovascular Medicine.

Dr Bilazarian performs coronary and peripheral interventions at Lahey Clinic and Massachusetts General Hospital. He has been an investigator in the interventional laboratory for new devices including drug-eluting stents, distal protection devices, imaging devices (OCT and InfraRed), and anticoagulant pharmacotherapy.

Dr Bilazarian is an active participant in clinical trials in congestive heart failure, hypertension, coronary disease prevention, prediabetes management, anemia, atrial fibrillation, and anticoagulation/antiplatelet therapies in the outpatient setting. He has authored numerous papers and book chapters in clinical cardiology. He was appointed as a physician advisor to the circulatory device panel of the FDA in 2008.
About this blog
My intent is to create a forum for dialogue on issues pertinent to private practice cardiology around topics such as:

  • Integration of new data and guidelines on inpatient and outpatient practice in clinical and interventional cardiology
  • Practice approaches to the extra clinical issues in dealing with managed care insurers
  • Strategies for navigating the restrictions of pharmacy benefits managers (PBMs) on pharmacologic therapies for our patients
  • Experiences with restrictions on testing and imaging
The video blog (VLOG) will provide an opportunity to share broadly different approaches to the common conundrums we face in caring for patients. My hope is that this forum will provide useful data points for practice outside of tertiary and academic centers and a look inside community hospitals and physician?s practice patterns in the office, starting with mine.