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Lipoprotein(a): a causal factor for coronary diseaseJan 7, 2010 10:30 EST
A striking and impressive study of the genomics of CAD raises practical questions: should we be measuring LPA genetic variants to assess the risk of coronary disease? Should Lp(a) levels be modulated with drugs such as niacin or other alternatives?
Clarke R, Peden JF, Hopewell JC et al. Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med 2009; 361: 2518-2528. Available at: www.nejm.org.