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PLATO, CURRENT-OASIS 7, and further analyses of PPIs and thienopyridines; read Dr Prasad's review of recent data presented at ESC; and watch presentations by Drs Mehran, O'Donoghue, Storey, and Wiviott.
In the US, each year over 1.4 million people will be hospitalized for unstable angina (UA) and non-ST-segment-elevation myocardial infarction (NSTEMI). Multiple antiplatelet agents have been developed to interfere with or inhibit the specific pathways of platelet activation and aggregation that lead to the development of UA and NSTEMI. Join Drs Newby, Popma, and Wiviot as they discuss.
PLATO, the ESC late-breaking trial, compared a novel direct-acting reversible P2Y12 antagonist with clopidogrel in ACS patients undergoing PCI. Dr. Keith Fox leads a discussion with the PI, Dr. Lars Wallentin, and Dr. Deepak Bhatt.
With the recent approval of a third-generation thienopyridine, choice of agent can be added to the list of considerations in the management of ACS patients, as well as the appropriate timing and dosing of thienopyridine. Using some case vignettes, Dr. King leads a discussion with Drs. Bhatt and Steg on their clinical decision-making.
Patients presenting with STEMI represent a high-risk population. Thrombotic and bleeding complications contribute to mortality in these patients. Join Drs. Steg, Hamm, Hill, and Mehran as they discuss best practices for the treatment of STEMI patients with a focus on preventing bleeding complications.
Antiplatelet therapy is key for the prevention of secondary events in ACS patients. Dr. Ardissino introduces a series of brief presentations by Drs. Angiolillo, Fernánadez-Avilés, Montalescot, and Neumann on the optimal use of antiplatelets in ACS patients undergoing PCI, including those with diabetes and those at high bleeding risk.
How will the prasugrel approval and the upcoming PLATO and CURRENT-OASIS 7 trials affect antiplatelet options for ACS patients undergoing PCI? Read a summary of the latest data, with expert input from Drs. Ardissino and Montalescot.
A patient suffers a STEMI after exploratory laparotomy for suspected gastrinoma; their surgeon insists that no anticoagulation be given. How would you treat? Dr. Rao presents such a complicated case to Dr. Montalescot.
Management of long-term anticoagulation therapy in STEMI patients is challenging. Please join our expert panel, Drs. Elaine Hylek, Ander Cohen, Greg Lip, and Jack Ansell, as they discuss current challenges and strategies to optimize the benefit of and provide insights to the future of anticoagulation therapy.
The treatment options for oral anticoagulation therapy are constantly evolving. Join our expert panel, Drs. Graham Turpie, Jessica L. Mega, Jeffrey Weitz, as they discuss the new data and clinical implications of new anticoagulant medications for patients with ACS
From SOLACI 2009 in Rio de Janeiro. Dr. Mahmud hears how Dr. Feres interprets the data on antiplatelet/antithrombin strategies for his practice in Brazil.
HORIZONS-AMI has influenced US practice; after TRITON-TIMI 38, the potential role of prasugrel is a hot topic. How has Latin America responded to these data? Recorded at SOLACI 2009, Dr. Mahmud has an information exchange on contemporary antiplatelet management with two of Argentina's leading interventionalists, Drs. Grinfeld and Londero.
As innovative research expands and unfolds, management of the patient with acute coronary syndrome continually takes on new dimensions. Join Dr. Eugene Braunwald and other experts as they delve into current and future pharmacotherapeutic strategies and issues surrounding the best practices for ACS patients.
Recently published data suggest that prior polyvascular disease increases the risk for inhospital adverse events in patients with ACS. Join Drs. Deepak Bhatt, Jean-Pierre Bassand, and José R. Gonzalez-Juanatey for a discussion of the current data on identification and management of patients with polyvascular disease.
AF can lead to stroke, congestive heart failure, and other serious complications. Successful management should include reducing these risks. Join our expert panel, Drs. Peter Rothwell, Donald Easton, and Mark Alberts, as they discuss new data and strategies for improving outcomes in patients with AF.
After EARLY-ACS and HORIZONS-AMI, the utility of routine GP IIb/IIIa inhibitors in contemporary management of ACS patients has been challenged. Studies of prehospital and pre-angiography administration have yielded mixed results, largely reflecting different trial designs. Dr. Gershlick aims to clarify matters with Drs. Hamm and Mehran.
Studies suggest that major bleeding is associated with a 5-fold increase in the risk for death among ACS patients. Join our expert panel: Profs. Hamm, Kristensen, and Spaulding as they discuss treatment options and strategies to reduce bleeding in STEMI patients.
Despite modern therapy, the rates of death, MI, bleeding, and readmission remain high in patients with ACS. Join Drs. Jeffery Popma, Héctor Bueno, Freek Verheugt, and Sunil. Rao for a review of the latest data on antiplatelet therapy for patients with ACS.
iQandA, The Interactive Medical Intelligence Zone is a needs assessment-driven continuing medical education (CME) activity that utilizes international experts to provide evidence-based, guideline-consistent, and practice behavior-changing information focused on critical and challenging topics in clinical medicine.
How can we reduce the time taken to accurately diagnose ACS? ECGs and biomarkers may be nondiagnostic, even the presenting symptoms can vary or be absent. As every 30 minutes delay is associated with a 7.5% relative increase in mortality, time is indeed muscle. Join Drs. Gibson, Pride, Santini, and Krucoff as they present new insights into this complex field.
Patients with diabetes have more reactive platelets and are also more likely to have a diminished response to antiplatelet therapy. Dr. Angiolillo presents Dr. Storey with a case illustrating issues in the management of antiplatelet therapy in an ACS patient with diabetes.
Join Drs. Harrington, Gibson, and Bates as they discuss the difficult issues of antithrombotic choices and the medical management of patients with NSTEMI.
Atrial fibrillation (AF) is the most frequently occurring cardiac arrhythmia affecting some 2.2 million Americans with often serious clinical consequences.. Join Drs. Bhatt, Connolly and Camm for a discussion on the risk factors, management challenges, and new data on treatment options for patients with AF
Carriers of certain CYP genetic variants have lower levels of clopidogrel's active metabolite and experience higher rates of MACE. Could genotyping help optimize antiplatelet therapy? Common PPIs also inhibit CYP enzymes and may impair clopidogrel efficacy. Dr. Topol discusses recent data on these topics with Drs. Montalescot, Sabatine, and Simon.
PLATO, CURRENT-OASIS 7, and further analyses of PPIs and thienopyridines; read Dr Prasad's review of recent data presented at ESC; and watch presentations by Drs Mehran, O'Donoghue, Storey, and Wiviott.
PLATO, CURRENT-OASIS 7, COGENT, recent meetings have seen some blockbuster presentations in the area of antiplatelet/antithrombotic therapy. What is your response to these data? Answer our 4 short polling questions and learn your peers' responses.
Patients presenting with STEMI represent a high-risk population. Thrombotic and bleeding complications contribute to mortality in these patients. Join Drs. Steg, Hamm, Hill, and Mehran as they discuss best practices for the treatment of STEMI patients with a focus on preventing bleeding complications.
In the US, each year over 1.4 million people will be hospitalized for unstable angina (UA) and non-ST-segment-elevation myocardial infarction (NSTEMI). Multiple antiplatelet agents have been developed to interfere with or inhibit the specific pathways of platelet activation and aggregation that lead to the development of UA and NSTEMI. Join Drs Newby, Popma, and Wiviot as they discuss.
Management of long-term anticoagulation therapy in STEMI patients is challenging. Please join our expert panel, Drs. Elaine Hylek, Ander Cohen, Greg Lip, and Jack Ansell, as they discuss current challenges and strategies to optimize the benefit of and provide insights to the future of anticoagulation therapy.