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Only 101 of 1169 post-bypass-surgery patients eligible for an ICD got one over a 13-year period in Nova Scotia.
Edmonton, AB - A 13-year study of bypass-surgery patients in Nova Scotia shows that only about one in 10 patients who are eligible for an implantable defibrillator ever got one, and the rate is particularly low in women and the elderly, due mainly to inconsistent patient follow-up [1].
Results of the study were presented here by medical student Ryan Kelly (Dalhousie University, Halifax, NS) at the Canadian Cardiovascular Congress 2009.Read full article »
Inside: Arrhythmia/EP
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Dr. Ileana Piņa discusses the design and outcomes of the MADIT-CRT trial with Drs. Moss and Estes, and how these new data may benefit patients with heart failure.
Does early intervention with CRT-D slow the progression of heart failure? Watch as Dr. David Cannom interviews Drs. Camm, Hlatky, Klein, Moss and Page, and gets their expert opinions on late-breaking clinical trial data released at ESC 09 and how it will affect patient care.
Rate control, rhythm control, new drugs and devices for anticoagulation -- the armamentarium of treatment options is expanding rapidly. Drs. Yancy, Cannon, and Boehmer discuss the latest treatment modalities for patients with AF.
Read Dr. Jonathan Piccini's review of prevention of stroke in AF and how the newly released results of clinical trials of novel antithrombotic agents will reduce the risk for stroke. Then listen to our international panel of experts, Drs. Camm, Granger, Prystowsky, and Yusuf, as they give their take on new data released at ESC 2009.
Join our international panel of experts, Drs. Lip, Halperin, Weitz, Ezekowitz, Wallentin, and Connolly as they present late-breaking results of the RE-LY trial.
Evidence-based therapies, both pharmacologic and devices are well documented in published guidelines, but are they followed and implemented in practice? Is there a treatment gap? Is it all about education or the lack thereof? Drs. Yancy, Abraham, and Pfeffer confer on evidence from recent registries and trials.
The results of MADIT-CRT suggest patients with early stage (NYHA class I/II) symptomatic heart failure (HF) indicated for an implantable cardioverter defibrillator (ICD) may benefit from the addition of cardiac resynchronization therapy (CRT). How likely are these results to increase device implant rates? Take our poll and see how your colleagues responded.
Atrial fibrillation is associated with a high risk for stroke, myocardial infarction, heart failure, and death. How does blockade of the renin-angiotensin system affect patient outcomes? Join our international panel of experts, Drs Camm, Connolly, Crijns, and Granger, as they discuss the ESC 09 hotline results of the ACTIVE-I trial.
Dr. Jeroen Bax, on the cusp of publishing a landmark paper to validate the role of MIBG imaging in risk stratifying patients with heart failure, provides a snapshot of his study in this interview from Europace 2009.
How can we reduce the time taken to accurately diagnose ACS? ECGs and biomarkers may be nondiagnostic, even the presenting symptoms can vary or be absent. As every 30 minutes delay is associated with a 7.5% relative increase in mortality, time is indeed muscle. Join Drs. Gibson, Pride, Santini, and Krucoff as they present new insights into this complex field.
Atrial fibrillation (AF) is the most frequently occurring cardiac arrhythmia affecting some 2.2 million Americans with often serious clinical consequences.. Join Drs. Bhatt, Connolly and Camm for a discussion on the risk factors, management challenges, and new data on treatment options for patients with AF
No survival differences after out-of-hospital cardiac arrest were seen at a preliminary DSMB review in the ROC PRIMED trial, which compared early vs delayed post-CPR assessment for defibrillation and tested the effectiveness of a device for optimizing intrathoracic pressure during CPR.
Long work shifts with nighttime on-call duty, with the inevitable interruptions of sleep, are associated with ECG, blood-pressure, and biochemical changes associated with increased cardiovascular risk, suggests a randomized crossover study that hints at a sustained effect on the risk markers if the 24-hour shifts happen too frequently.
A US update on the perioperative use of beta blockers for noncardiac surgery is, says the lead author, "similar" to recent European guidance on this issue.
An additional year of data from the INCREMENTAL study showed that echo-targeted LV lead positioning increased the likelihood of a response to device therapy by about 40% over standard lead placement. But does that difference translate into better long-term outcomes for the patient?
The fact that elevated baseline NT-proBNP levels predict a diagnosis of AF even 16 years later suggests that peptide elevations precede the onset of arrhythmia, according to the researchers.
With few studies in the literature specifically looking at the issue, a prospective, population-based study in Sweden has found no significant rise or fall in risk of heart-failure hospitalization or death at increasing levels of coffee intake.
Two-thirds of the 156 trials considered by the AHA in preparing a recent guideline failed to even record the ethnic backgrounds of participants, a new study has found. The researchers call for the reporting of race/ethnicity to be mandatory in all clinical trials, and they suggest medical journals should enforce this policy.
Are the data not shouting loud enough, or is cardiology hard of herring? Omega-3 fatty acids may have only a modest treatment effect in heart failure, but they've performed swimmingly in randomized and observational studies considering how few new HF drugs have been reeled in lately.
In a case-control study from Denmark, the risk of atrial fibrillation or flutter was significantly increased with current but not previous use of glucocorticoids for chronic obstructive pulmonary disease, rheumatoid arthritis, and other conditions.
How do regulatory pathways differ in the US and UK? Drs Harrington, Bhatt, and Cleland share their experiences and offer insight on how to support innovative research.
Dr Melissa Walton-Shirley talks to Dr Nassir Marrouche about the results of RE-LY, the impact of dronedarone on the treatment of atrial fibrillation, and his hopes for the future of MRI-guided ablation.
Join 'heartwire's Steve Stiles as he talks to Drs Nassir Marrouche and Clyde Yancy about MADIT-CRT, the potential benefits and costs for the heart-failure population in light of the trial, and about why the Europeans seem to be ahead of the guidelines in the European CRT Survey.