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The imaging study was the first to show that stenting a non-flow-limiting stenosis of an SVG may help slow or halt the accelerated atherosclerosis that takes place in these vessels. An accompanying editorial cautions that the study does little more than "infer a trend toward anatomic benefit."
Dallas, TX - Results of the ambitious and controversial "plaque-sealing" VELETI trial, looking at prophylactic use of paclitaxel-eluting stents in non-flow-limiting stenoses of saphenous vein grafts (SVGs), has now been published online November 2, 2009 in Circulation [1], accompanied by an editorial calling the strategy "ahead of its time [2]."
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Inside: Interventional/Surgery
Accredited educational programs,
supported by industry, developed by theheart.org
Since BARI, CABG has been the gold standard for patients with diabetes and multivessel disease. However, SYNTAX suggests an increasing role for PCI and BARI 2D highlights the importance of optimal medical therapy. Dr. Boden leads a multidisciplinary discussion with Drs. Holmes and Taggart.
With the recent approval of a third-generation thienopyridine, choice of agent can be added to the list of considerations in the management of ACS patients, as well as the appropriate timing and dosing of thienopyridine. Using some case vignettes, Dr. King leads a discussion with Drs. Bhatt and Steg on their clinical decision-making.
Dr. Dean Kereiakes leads an international panel of experts, Drs. Meredith, Banning, and Hermiller, as they discuss fascinating developments in stent and polymer technology and design their "dream stent."
How do the results of the SYNTAX trial impact clinical practice now? Join Drs. Banning and Hill as they present a complex case taken directly from the SYNTAX trial and discuss how new data will impact their choice of treatment, and listen to an overview of the trial presented by Dr. William Wijns.
The PARTNER and PAVIS trials of transcatheter aortic valve implementation will include inoperable or very high-surgical-risk patients. In Europe, where the devices have been approved for a few years, the technology is being expanded to lesser-risk patients. Interventionalist Dr Jeffrey Popma discusses the selection of patients with surgeon Dr Mathew Williams.
Transcatheter aortic valve implantation (TAVI) has been approved in Europe since 2007, whereas these devices are just entering large-scale research trials in the United States. Dr. Popma leads a panel discussion with European interventionalist Dr. Eberhard Grube and surgeon Dr. Neil Moat on their experiences with TAVI.
How do drug-eluting stents compare? Our panel of experts, Drs. Stone, Kereiakes, Serruys, and Windecker discuss the late-breaking trials at TCT 2009 of DES vs DES.
How do drug-eluting stents compare? Our panel of experts, Drs. Stone, Kereiakes, Serruys, and Windecker discuss the late-breaking trials at TCT 2009 of DES vs DES.
Recently published data suggest that prior polyvascular disease increases the risk for inhospital adverse events in patients with ACS. Join Drs. Deepak Bhatt, Jean-Pierre Bassand, and José R. Gonzalez-Juanatey for a discussion of the current data on identification and management of patients with polyvascular disease.
AF can lead to stroke, congestive heart failure, and other serious complications. Successful management should include reducing these risks. Join our expert panel, Drs. Peter Rothwell, Donald Easton, and Mark Alberts, as they discuss new data and strategies for improving outcomes in patients with AF.
Despite modern therapy, the rates of death, MI, bleeding, and readmission remain high in patients with ACS. Join Drs. Jeffery Popma, Héctor Bueno, Freek Verheugt, and Sunil. Rao for a review of the latest data on antiplatelet therapy for patients with ACS.
The latest recommendations for the treatment of ST-elevation MI issued by American cardiology associations and the European Society of Cardiology are compared and contrasted in a new paper.
A 2203-patient randomized trial of off-pump vs on-pump CABG surgery found no differences in neuropsychological outcomes and worse overall outcomes for the off-pump group at one-year follow-up.
In keeping with all the other evidence showing no effects of homocysteine-lowering with B vitamins, the FAVORIT study now confirms that this lack of benefit is also seen in renal-transplant recipients.
Dr David Gossman has filed a lawsuit claiming that he was fired for complaining about ties between the hospital and some of its senior staff with the medical device company Medtronic.
A US update on the perioperative use of beta blockers for noncardiac surgery is, says the lead author, "similar" to recent European guidance on this issue.
Researchers in Ottawa find that the longevity of porcine replacement heart valves may depend partly on whether the blood type of the patient matches the blood type of the valve's "original owner."
After a median follow-up of 12 years, MI rates were essentially the same among those treated with surgery and those who received conventional care for weight loss.
Women and men have the same rates of chest pain and other classic symptoms during ACS, although women are more likely to experience some other symptoms such as jaw and neck pain.
Speaking at the 30th anniversary of the GISE Congress, Palmaz said he'd never believed drug elution was the way forward for stents and outlined his theories for why coatings of any kind disrupt the healing properties of metallic coronary stents.
Raised in a blue-collar neighborhood of Somerville, MA, Dr Bob Harrington was blessed to have a strong family and the Jesuits on his side as he traveled from "Yankee" Boston to Duke University. Join him as he tells his story to Dr Rob Califf.
How do regulatory pathways differ in the US and UK? Drs Harrington, Bhatt, and Cleland share their experiences and offer insight on how to support innovative research.
With the ISIS-1 trial, Dr Peter Sleight and his team at Oxford changed the approach to cardiovascular research. Join Dr Robert Califf as he talks to Dr Sleight about his journey from London to San Francisco to Oxford and finally to Italy, where he discovered the music of the heart.