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heartbriefs
Nov 20, 2009 13:15 EST
As part of his mission to see more financial transparency in medicine, Sen Grassley has asked eight top US medical schools about their policies on ghostwriting.
Medscape Medical News
2 COMMENTS - Nov 20, 2009 13:00 EST
Mayo Clinic researchers report that their stroke rate related to PCI has stayed steady for the last 15 years, something they interpret as good news, given that substantially older, sicker patients with more complex anatomy are now undergoing PCI.
Acute Coronary Syndromes
Nov 19, 2009 11:00 EST
A dose-finding study saw what were characterized as low bleeding rates associated with triple-drug antithrombotic therapy that included the oral anticoagulant dabigatran in patients with a recent ACS event and other cardiovascular risk factors.
News
Nov 19, 2009 10:00 EST
Publicly released report cards based on hospital performance did not result in a measurably greater systemwide improvement in two composite AMI or CHF process-of-care indicators in a Canadian study. But they did appear to stimulate some important changes in delivery of care that could have led to some better outcomes.
Interventional/Surgery
1 COMMENT - Nov 18, 2009 15:45 EST
New data from the BARI 2D trial comparing medical therapy vs revascularization in diabetics shows higher up-front costs of revascularization are only partially offset by long-term savings.
Thrombosis Risk
Nov 18, 2009 15:00 EST
New and unique phase 2 data add to the growing body of evidence explaining the pharmacologic effects of the new antiplatelet agent ticagrelor.
Interventional/Surgery
Nov 18, 2009 10:45 EST
Measures of left ventricular dysfunction or wall motion identified by different imaging modalities at baseline offer no clues as to whether a subset of patients treated with surgical ventricular reconstruction might benefit from the procedure.
Acute Coronary Syndromes
9 COMMENTS - Nov 18, 2009 09:00 EST
The latest evidence for the treatment of STEMI and PCI has been incorporated into a fast-track update of US guidelines. But questions remain about the quality of some of the evidence informing the guidelines and about the composition of the writing committees.
Interventional/Surgery
Nov 17, 2009 10:00 EST
Mean pericardial effusion grade postcardiac surgery was not reduced with 14 days of treatment with the NSAID.
Interventional/Surgery
4 COMMENTS - Nov 17, 2009 09:00 EST
Dual antiplatelet therapy did not significantly reduce vein graft intimal hyperplasia compared with aspirin alone over 12 months.
Heart failure
Nov 17, 2009 08:00 EST
UPDATED WITH COMMENTARY // Thoratec's HeartMate II continuous-flow VAD keeps about half of patients alive and stroke- or reintervention-free after two years in pivotal destination therapy trial.
Brain/Kidney/Peripheral
Nov 16, 2009 18:45 EST
Depression after coronary artery bypass surgery is often overlooked by physicians but is associated with worse outcomes. A new US study illustrates a simple telephone-based approach to tackle this, with nurses encouraging patients to seek help from their primary-care doctors and providing ongoing feedback and review.
Interventional/Surgery
Nov 16, 2009 17:45 EST
A randomized trial found no protection from in-hospital cardiovascular events with a strategy of blood transfusions to maintain hemoglobin above 10 g/dL, compared with a more conservative approach to transfusion therapy, in patients with CV disease or risk factors who underwent hip surgery.
Interventional/Surgery
Nov 16, 2009 16:15 EST
Data from a Massachusetts registry add to the growing evidence that hospitals without bypass-surgery capabilities can match the acute coronary intervention outcomes of surgery-on-site centers.
Acute Coronary Syndromes
2 COMMENTS - Nov 16, 2009 15:15 EST
Discussion is abounding on why cangrelor did not show benefit over clopidogrel despite the fact that it did inhibit platelet activity more effectively.
Acute Coronary Syndromes
1 COMMENT - Nov 15, 2009 19:30 EST
Ticagrelor, an investigational antiplatelet agent, may become a new standard of care for the management of patients with STEMI heading for primary PCI, said the lead investigator of the STEMI subset of the PLATO trial. Reporting the new findings here today, he said they were consistent with the overall PLATO results.
Thrombosis Risk
Nov 15, 2009 14:15 EST
None of the eight platelet assays studied were able to predict bleeding, but four of the eight, based on ADP-induced platelet aggregation, produced results that correlated with adverse CV outcomes. By contrast, four tests that use shear-stress-induced adhesion-based methods were not predictive.
Interventional/Surgery
Nov 15, 2009 10:30 EST
Inflation of the paclitaxel-delivering balloon followed by a bare-metal stent failed a randomized noninferiority test against the Cypher sirolimus-eluting stent in previously untreated coronary lesions.
Interventional/Surgery
Nov 15, 2009 09:45 EST
Results from one of the first registries to evaluate contemporary use of both the Edwards Sapien transcatheter valve and the CoreValve bioprosthesis show that complication rates are low and similar, following a short training period, and that mortality, at least out to six months, is "acceptable" for both types of devices.
Interventional/Surgery
Nov 15, 2009 09:00 EST
Two-year follow-up results from the EXPIRA study show mechanical thrombectomy during primary PCI improves myocardial perfusion and may reduce mortality.
Interventional/Surgery
5 COMMENTS - Nov 15, 2009 08:30 EST
Experienced interventional cardiologists can rapidly shift their practice from the femoral-artery to the radial-access approach, with no increase in procedure time and radiation exposure for PCI. Also, the transradial approach leads to a more economic use of hospital resources, say researchers.
Acute Coronary Syndromes
2 COMMENTS - Nov 15, 2009 08:00 EST
Although neither CHAMPION-PCI nor CHAMPION-PLATFORM showed significant reductions in the primary end point with this new IV antiplatelet agent, some positive effects were seen, suggesting that the drug may yet have a future.
Medscape Medical News
Nov 12, 2009 15:00 EST
Now that the US House of Representatives has passed a healthcare reform bill, organized medicine anticipates another vote—possibly next week—on a second bill that would rewrite Medicare's controversial sustainable-growth-rate formula for physician reimbursement.
Interventional/Surgery
4 COMMENTS - Nov 12, 2009 13:15 EST
A new postmortem study using high-resolution imaging has found that fractures in drug-eluting stents may be more common than thought. However, the majority of such fractures appear to be low-grade and silent, with likely few clinical implications, say the researchers.
Interventional/Surgery
9 COMMENTS - Nov 11, 2009 17:00 EST
Percutaneous revascularization of atherosclerotic renal arteries improves patency, but its benefits on renal function have been evaluated only in small studies. The 806-patient ASTRAL trial found no evidence of benefit from revascularization.

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