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heartbriefs
Medicaid access to smoking cessation falls short
Nov 5, 2009 17:30 EST
A national survey shows that although the majority of state Medicaid programs offer coverage for some form of tobacco-dependence treatment, most fall far short of a stated mandate to provide unrestricted access to approved therapies.
Medscape Medical News
Low-cholesterol/cancer studies should "dispel lingering doubts" of causal link
Nov 5, 2009 14:15 EST
Two new papers should help put to rest concerns that low serum cholesterol levels may increase cancer risk.
Lipid/Metabolic
Not all metabolic syndrome is created equal: Framingham Offspring analysis
Nov 5, 2009 11:45 EST
The syndrome (defined by ATP III criteria) can predict increased cardiovascular and mortality risk or not, depending on which three of five risk factors contributed to the diagnosis, a cohort study suggests; its investigators caution that their observations are only preliminary.
Hypertension
Adding fuel to the J-curve fire; debate is reignited
2 COMMENTS - Nov 4, 2009 14:30 EST
More discussion about the J-curve in hypertension is published this week; one expert believes the undue attention being paid to this subject might discourage doctors from treating high blood pressure aggressively.
heartbriefs
No CV risk reduction with B vitamins posttransplant
Nov 4, 2009 13:15 EST
In keeping with all the other evidence showing no effects of homocysteine-lowering with B vitamins, the FAVORIT study now confirms that this lack of benefit is also seen in renal-transplant recipients.
Prevention
Another in-hospital CV risk marker: 24-hour shifts with overnight on-call duty
1 COMMENT - Nov 4, 2009 09:45 EST
Long work shifts with nighttime on-call duty, with the inevitable interruptions of sleep, are associated with ECG, blood-pressure, and biochemical changes associated with increased cardiovascular risk, suggests a randomized crossover study that hints at a sustained effect on the risk markers if the 24-hour shifts happen too frequently.
Imaging
CAC scoring plus SPECT provide long and short view of cardiac risk
6 COMMENTS - Nov 3, 2009 17:00 EST
UPDATED // An 1126-patient trial shows that SPECT and CAC scoring imaging tests are independent and complementary predictors of short- and long-term cardiac risk, respectively.
Hypertension
Combined home/GP hypertension control program successful in Pakistan
3 COMMENTS - Nov 2, 2009 17:00 EST
A synergistic approach of educating general practitioners about hypertension control together with a program to send lay workers into people's homes to educate them about the management of high blood pressure has proven successful in low- to middle-income households in Pakistan.
Prevention
Advocates build support for Canadian Heart Health Strategy in a difficult environment
Nov 2, 2009 11:15 EST
Supporters of the Canadian Heart Health Strategy and Action Plan continue to solicit support from physicians and the public for a comprehensive strategy for improving Canadian's heart health at both the provincial and federal level.
Imaging
Imaging study shows plaque regression with niacin vs placebo
15 COMMENTS - Oct 30, 2009 16:00 EDT
Just weeks before ARBITER-HALTS 6 results come out at AHA 2009, an MRI study suggests that niacin is better than placebo in statin-treated patients with low HDL, at least for reducing carotid wall area. Experts say they'd also like to see insights into niacin effects on lipid-rich plaque volumes—the more commonly seen end point with MRI.
Lipid/Metabolic
Lifestyle-based diabetes prevention seen to endure for at least a decade
Oct 30, 2009 10:00 EDT
The protective effects of diet modification, exercise, and other lifestyle changes against new-onset diabetes showcased in the three-year Diabetes Prevention Program continued out to 10 years in a follow-up analysis.
Acute Coronary Syndromes
Sex differences in changing MI prevalence, mortality challenge conventional wisdom
Oct 29, 2009 10:30 EDT
Two well-known observational registries highlight such changes in women and men over a decade or more: Do women younger than 55 still have an advantage over men in the same age group?
Acute Coronary Syndromes
Bariatric surgery fails to reduce risk of MI long term
1 COMMENT - Oct 28, 2009 14:30 EDT
After a median follow-up of 12 years, MI rates were essentially the same among those treated with surgery and those who received conventional care for weight loss.
Prevention
Lorcaserin passes weight-loss and valvular hurdles in BLOSSOM study
1 COMMENT - Oct 27, 2009 16:15 EDT
Among overweight patients, including those with preexisting echocardiographic valvulopathy, the average weight loss was approximately 5 kg with lorcaserin. Importantly, there were no concerns raised about new or worsening cardiac valve problems with the 5HT2C-receptor agonist.
Prevention
Experts weigh in on calorie lists on menus, despite "mixed" science
2 COMMENTS - Oct 26, 2009 16:45 EDT
Results showing that people eat less when they know how many calories are in that Big Mac are mixed, but experts say that menu labeling provides only upside, with no public-health cost, and that over time results will show the information to have a positive effect on obesity rates in the US.
heartbriefs
Distribution of body fat important in VTE
Oct 26, 2009 16:00 EDT
The distribution of body fat, as well as the amount, is important when it comes to the risk of venous thromboembolism, Danish researchers have discovered.
Lipid/Metabolic
Less exposure to cardiovascular risk factors with intensive diabetes intervention: Look AHEAD
1 COMMENT - Oct 26, 2009 10:00 EDT
Intensive lifestyle intervention in the management of diabetes produces sustained weight loss and improvements in fitness, as well as improvements in glycemic control, systolic blood pressure, and HDL-cholesterol levels.
Lipid/Metabolic
New MESA data: Pericardial fat a better predictor of CHD than BMI
9 COMMENTS - Oct 23, 2009 17:00 EDT
Pericardial fat, which is found around the heart, predicts future CHD events and may even be a better predictor of these than conventional obesity measures, such as BMI and waist circumference, a new study of MESA participants shows.
heartbriefs
New model connects low-dose radiation to CVD risk
Oct 23, 2009 15:30 EDT
Data from Japanese atomic-bomb survivors and people exposed to radiation in their jobs show that even low doses of ionizing radiation may contribute to cardiovascular disease risk. British researchers have created a complex mathematical model to better understand the relationship between radiation exposure and heart disease.
Lipid/Metabolic
GLP-1 analog liraglutide promising in obesity
Oct 22, 2009 18:30 EDT
A drug originally developed to treat diabetes may have promise as an obesity therapy, a new study shows. Those taking liraglutide, a GLP-1 analog, lost more weight than those on an established obesity medication, orlistat.
Prevention
HCM transmitted by sperm donation: A case report
Oct 22, 2009 15:45 EDT
The donor, who was later shown to be affected by a novel beta-myosin heavy-chain mutation that causes HCM, is responsible for at least nine children known to be genetically affected with HCM.
Prevention
Glucose lowering in type 2 diabetes to prevent CVD remains controversial but still important
1 COMMENT - Oct 22, 2009 14:45 EDT
Although the case for intensive glucose lowering in diabetic patients to prevent CVD is not straightforward, glucose control is still important for other reasons, and blood pressure and lipid control should not be neglected, according to debaters at a diabetes meeting.
Prevention
Current risk equations may overestimate CVD risk in diabetic patients
Oct 21, 2009 10:00 EDT
Researchers using different international databases report that the Framingham and UKPDS risk equations overestimate the probability of CV events in diabetic patients.
Lipid/Metabolic
Thiazolidinediones have a role for appropriate diabetic patients
5 COMMENTS - Oct 20, 2009 12:45 EDT
After 10 years of clinical use of TZDs, "we are still at the beginning," and randomized controlled trials shed light on their use in appropriate diabetic patients, speakers at a diabetes symposium reported.
heartbriefs
Expanded indication for telmisartan
3 COMMENTS - Oct 19, 2009 13:30 EDT
The drug can now be used to reduce the risk of MI, stroke, or death from cardiovascular causes in patients 55 years of age or older who are intolerant to ACE inhibitors but at high risk for cardiovascular events.

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Medscape
Assessing Risk and Enhancing Response in Patients With Coronary Artery Disease: The Role of Genetics
Sep 18, 2009 16:16 EDT
The following test-and-teach case is an educational activity modeled on the interactive grand rounds approach. The questions within the activity are designed to test your current knowledge. After each question, you will be able to see whether you answered correctly and will then read evidence-based information that supports the most appropriate answer choice. Please note that these questions are designed to challenge you; you will not be penalized for answering the questions incorrectly. At the end of the case, there will be a short post-test assessment based on material covered in the activity.
Prevention
Assessing the Risk for Development of Heart Disease -- The Role of Genetics: An Expert Interview With John P. Kane, MS, MD, PhD
Sep 11, 2009 17:48 EDT
Genetic findings that affect the course of diseases have been increasing geometrically. Cardiology is one of the specialties that has benefited from recent discoveries. David Danar, MD, Scientific Director, MedscapeCME, interviewed John P. Kane, MS, MD, PhD, about the role of genetics in determining the risk for and management of heart disease.