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EAS 2011 - Gothenburg, Sweden

Heartwire

Lipid/Metabolic
Metabolic profiling early in life predicts subclinical atherosclerosis
5 COMMENTS - Jun 30, 2011 11:45 EDT
In a comparison of a prediction model that included metabolic profiling against a reference model that used conventional risk factors, researchers observed a slight increase in the area under the curve and a higher rate of reclassifying patients into different risk categories.
ESC/EAS tightens up lipid targets for dyslipidemia with new recommendations
Lipid/Metabolic
ESC/EAS tightens up lipid targets for dyslipidemia with new recommendations
18 COMMENTS - Jun 29, 2011 16:45 EDT
For patients at very high risk of cardiovascular disease, the ESC/EAS writing committee states that LDL-cholesterol levels should be lowered to less than 70 mg/dL, a target that is not optional, as it is in the NCEP guidelines. Even moderate-risk patients have a new target, that being less than 115 mg/dL, which is also lower than the NCEP guidelines. The task force believes there is a wealth of evidence supporting the "lower-is-better" LDL theory.
Lipid/Metabolic
HDL function, independent of levels, impaired in STEMI patients
3 COMMENTS - Jun 29, 2011 09:45 EDT
Investigators report that STEMI patients had reduced cholesterol-efflux capacity and an impaired inflammatory response, two markers indicative of impaired HDL function.
Lipid/Metabolic
Bariatric surgery reduces long-term MI risk in men, but not women
2 COMMENTS - Jun 28, 2011 14:30 EDT
Investigators report that bariatric surgery was associated with a significant 71% reduction in the risk of MI compared with control therapy in obese diabetic men, but not in women. That said, they suspect a lack of statistical power, the result of too few clinical events in the premenopausal women, is to blame for the difference between genders.
Lipid/Metabolic
New EAS consensus statement on high triglycerides, low HDL cholesterol
15 COMMENTS - Jun 27, 2011 16:15 EDT
Despite the recent failure of AIM-HIGH, as well as ACCORD-Lipid and FIELD, niacin and fibrates are the drugs of choice for treating patients with high triglycerides and low HDL-cholesterol levels. That said, authors of the new report urge that patients adopt healthier lifestyles, pushing for diet and exercise first to alter the adverse lipid profile.

Discussion and opinions