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A Food and Drug Administration advisory panel is set to review data and vote on an expanded indication for the RX Acculink Carotid Stent System. The expanded indication would see patients at standard risk for adverse events from endarterectomy become candidates for stenting.
Experts warned that it is important to clearly define the link between "venous insufficiency" and MS and that interventionalists and MS experts must answer the remaining unknowns given the high level of public interest in the procedure and the new era of regulation and medical cost containment.
The use of ultrasound energy is designed to loosen and thin the fibrin strands of the pulmonary clot, increasing permeability and thrombolytic penetration when drug therapy is administered, according to investigators. This helps the drug work faster and clears the clot sooner, all while using a lower dose of tPA.
A group reported that EVAR treatment with CO2 as the contrast agent resulted in a significant reduction in postoperative creatinine clearance but failed to reduce the incidence of renal failure.
An indication for carotid artery revascularization is an indication for stenting, says one expert, although he is quick to caution that treating octogenarians with stenting is a procedure best left only to experienced operators.
Drs Claudio Schonholz and Nelson "Nick" Hopkins argued for flow-reversal/proximal-occlusion devices and filters, respectively. One expert, however, said the issue remains unresolved until better measures of embolization, and what these translate into clinically, are developed.
Follow-up data in a study of peripheral endovascular therapy for the treatment of femoropopliteal disease confirms the positive results observed at 12 months, with investigators showing the Zilver PTX stent superior to both percutaneous transluminal angioplasty and the Zilver bare-metal stent.
