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Acute coronary syndrome patients should be discharged on the maximum tolerated doses of ACE inhibitors, beta blockers, and statins, data from a single European center suggest. Patients treated with the higher doses of the three agents had significantly lower mortality rates at one-year follow-up than those who were treated with low or intermediate doses.
The researchers showed that the engineered myocardial tissue shares structural and functional similarities with native myocardial tissue, including testing positive for troponin I.
Ten risk factors are associated with 90% of the risk of stroke; of these modifiable risk factors, hypertension is the most important for all stroke subtypes and is a particularly dangerous risk factor for intracerebral hemorrhage.
The clinical usefulness of a multiple biomarker index, one that includes markers of inflammation, depends on atherosclerotic disease burden, according to the results of a new study. The increased risk of events for asymptomatic patients with a biomarker score above the median occurs mainly in those with a mild amount of atherosclerosis disease, report researchers.