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LBCT.01 - Practice Implications for CAD and VTE
Dimanche 4 novembre, 15 h 30 – 17 h 20
Moderateurs:
Elliott Antman, Boston, MA, É.-U.
Frans Van de Werf, Louvain, Belgique
Gary H Gibbons, Bethesda, MD, É.-U.

		Aspirin for the Prevention of Recurrent Venous Thromboembolism After a First Unprovoked Event: Results of the ASPIRE Randomized Controlled Trial Timothy Brighton, South Eastern Area Lab Services (SEALS), Prince of Wales Hospital, Sydney, Australie Discussion : Mary Cushman, Colchester, VT , É.-U.
		A Randomized Trial of Bedside Platelet-Function Monitoring to Adjust Antiplatelet Therapy vs Standard of Care in Patients Undergoing Drug-Eluting Stent Implantation: The ARCTIC Study Gilles Montalescot, Hôpital La Pitié-Salpêtrière, Paris, France Discussion : Eric R Bates, Ann Arbor, MI, É.-U.
		First Large-Scale Platelet-Function Evaluation in an Acute Coronary Syndromes Trial: The TRILOGY ACS Platelet-Function Substudy Paul A Gurbel, Sinai Hospital Center for Thrombosis Research, Baltimore, MD, É.-U. Discussion : Lars Wallentin, Uppsala, Suède
		Results of the Trial to Assess Chelation Therapy Gervasio A Lamas, Mount Sinai Medical Center, Miami, FL, É.-U. Discussion : W Armstrong, Edmonton, AB, Canada
		Main Results of the Future Revascularization Evaluation in Patients with Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) Trial Valentin Fuster, Mount Sinai School of Medicine, New York, NY, É.-U. Discussion : Alice K Jacobs, Boston, MA, É.-U.

LBCT.02 - Health Economics and Quality of Life in Contemporary Trials
Dimanche 4 novembre, 17 h 30 – 18 h 45
Moderateurs :
Mikhail Kosiborod, Kansas City, MO, É.-U.
Fausto Pinto, Lisbonne, Portugal

		Prospective Evaluation of Outcomes With Stress Perfusion Imaging vs Stress Wall Motion Imaging During Dobutamine or Exercise Echocardiography Thomas R Porter, University of Nebraska Medical Center, Omaha, É.-U. Discussion : Gerald M Pohost, Los Angeles, É.-U.
		Economic Outcomes of Percutaneous Coronary Intervention Performed at Sites With and Without On-Site Cardiac Surgery Eric L Eisenstein, Duke Clinical Research Institute, Durham, NC, É.-U.
		Quality-of-Life Outcomes in the Trial to Assess Chelation Therapy (TACT) Daniel B Mark, Duke University Medical Center, Durham, NC, É.-U.
		Cost-Effectiveness of PCI with Drug-Eluting Stents vs Bypass Surgery for Patients with Diabetes and Multivessel Coronary Artery Disease: Results from the FREEDOM Trial Elizabeth A Magnuson, Saint Luke's Mid America Heart Institute, Kansas City, MO, É.-U.
		Discussion : (Implications cliniques des essais CPORT-E, TACT et FREEDOM) David O Williams, Boston, MA, É.-U. Mark Hlatky, Stanford, CA, É.-U.

LBCT.03 - Treatments for Prevention of Cardiovascular Events: A Population Perspective
Lundi 5 novembre, 9 h 00 – 10 h 16
Moderateurs:
Donna K Arnett, Birmingham, AL, É.-U.
William Zoghbi, Houston, TX, É.-U.

		Omega-3 Fatty Acids for the Prevention of Recurrent Symptomatic Atrial Fibrillation: Results of a double-blind randomized clinical trial (FORWARD) Alejandro Macchia, Consorzio Mario Negri Sud, Santa Maria Imbaro, Italie Discussion : Christine Albert, Boston, MA, É.-U.
		Fish Oil for the Prevention of Post-Operative Atrial Fibrillation: The Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation (OPERA) Trial Roberto Marchioli, Consorzio Mario Negri Sud, Santa Maria Imbaro, Italie Discussion : Ali Oto, Ankara, Turquie
		A Randomized Trial of a Multivitamin in the Prevention of Cardiovascular Disease in Men: The Physicians' Health Study II Howard D Sesso, Brigham and Women's Hospital, Boston, MA, É.-U. Discussion : Sidney C Smith, Chapel Hill, NC, É.-U.
		Use of a Multidrug Pill in Reducing Cardiovascular Events (UMPIRE) Simon A Thom, Imperial College London, R.-U. Discussion : Andrew M Tonkin, Melbourne, Australie

LBCT.04 - Novel Treatments for Managing Lipid Disorders
Lundi 5 novembre, 10 h 45 – 11 h 55
Moderateurs :
Robert H Eckel, Aurora, CO, É.-U.
Frank Sacks, Boston, MA, É.-U.

		Overview of PCSK9 Inhibition in the Treatment of Hyperlipidemia Jay Horton, University of Texas Southwestern, Dallas, É.-U.
		Reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD): Interim Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial Frederick Raal, University of Witwatersrand, Johannesburg, Afrique du Sud
		Goal Achievement after Utilizing an Anti-PCSK9 Antibody in Statin-Intolerant Subjects (GAUSS): Interim Results from a Randomized, Double-Blind, Placebo-Controlled Study Evan Stein, Metabolic and Atherosclerosis Research Center, Cincinnati, OH, É.-U.
		Effects of 12 Weeks of Treatment with RN316 (PF-04950615), a Humanized IgG2?a Monoclonal Antibody Binding Proprotein Convertase Subtilisin Kexin Type 9, in Hypercholesterolemic Subjects on High- and Maximal-Dose Statins Barry Gumbiner, Pfizer, San Diego, CA, É.-U.
		Discussion : (RUTHERFORD, GAUSS, et RN316) Peter Wilson, Atlanta, GA, É.-U.
		CaPre, A Novel Class of Omega-3 Phospholipids, Therapy in Patients With Mild-to-High Hypertriglyceridemia (from the Multicenter Placebo-Controlled, Randomized, Double-Blind 12-week Trial for Efficacy of CaPre on Hypertriglyceridemia [TRIFECTA]) Jacques Genest, Centre médical et universitaire McGill, Montréal, QC, Canada Discussion : Robert H Eckel, Aurora, CO, É.-U.
		Effects of the Cholesteryl Ester Transfer Protein Inhibitor Dalcetrapib in Patients with Recent Acute Coronary Syndrome Gregory G Schwartz, University of Colorado, Denver, É.-U. Discussion : Alan Tall, New York, NY, É.-U.

LBCT.05 - Cell-Based Therapies for Myocardial Regeneration
Lundi 5 novembre, 10 h 45 - 12 h 00
Moderateurs :
Stefanie Dimmeler, Francfort, Allemagne
Charles E Murry, Seattle, WA

		Overview of the Field of Cell-Based Therapies for Myocardial Regeneration Stefanie Dimmeler, Francfort, Allemagne
		Results of the Swiss Multicenter Intracoronary Stem Cells Study in Acute Myocardial Infarction (Swiss AMI) Trial Daniel Sürder, Fondazione Cardiocentro Ticino, Lugano, Suisse
		The ALCADIA (Autologous Human Cardiac-Derived Stem Cell to Treat Ischemic Cardiomyopathy) Trial Naofumi Takehara, Kyoto Prefectural University of Medicine, Kyoto, Japon
		The Effect of Timing of Stem-Cell Delivery Following Acute Myocardial Infarction: The NHLBI and CCTRN TIME Trial Jay H Traverse, Minneapolis Heart Institute, MN, É.-U.
		Comparison of Allogeneic vs Autologous Mesenchymal Stem Cells in Patients with Ischemic Cardiomyopathy Joshua M Hare, University of Miami Miller School of Medicine, FL, É.-U.
		Effect of Cardiac Stem Cells in Patients with Ischemic Cardiomyopathy: Interim Results of the SCIPIO Trial Up to 2 Years After Therapy Roberto Bolli, University of Louisville, KY, É.-U.
		Discussion des panélistes (incluant les modérateurs) : Marc S Penn, Akron, OH, É.-U. Joseph C Wu, Stanford, CA, É.-U. Philippe Menasché, Paris, France

LBCT.06 - Management of LV Dysfunction: Devices and Drugs
Mardi 6 novembre, 15 h 45 – 17 h 35
Moderateurs :
Mariell Jessup, Philadelphie, PA, É.-U.
Wilson Tang, Cleveland, OH, É.-U.

		MADIT Randomized Trial to Reduce Inappropriate Therapy (MADIT-RIT) Arthur J Moss, University of Rochester Medical Center, NY, É.-U. Discussion : Douglas P Zipes, Indianapolis, IN, É.-U.
		Biventricular vs Right Ventricular Pacing in Patients with Left Ventricular Dysfunction and Atrioventricular Block (BLOCK HF Study) Anne B Curtis, University at Buffalo, NY, É.-U. Discussion : Gerasimos S Filippatos, Athènes, Grèce
		Pilot Trial of Two Levels of Hypothermia in Comatose Survivors from Out-of-Hospital Cardiac Arrest Esteban Lopez-de-Sa, Hospital Universitario La Paz, Madrid, Espagne Discussant : Graham Nichol, Seattle, WA, É.-U.
		The Relaxin in Acute Heart Failure (RELAX-AHF) Trial John R Teerlink, San Francisco Veterans Affairs Medical Center, University of California, San Francisco Discussion : John McMurray, Glasgow, Écosse
		Cardiorenal Rescue Study in Acute Decompensated Heart Failure: Results of CARRESS-HF, for the Heart Failure Clinical Research Network Bradley A Bart, Hennepin County Medical Center, Minneapolis, MN, É.-U. Discussion : Milton Packer, Dallas, TX, É.-U.