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Interventional/Surgery
BP reductions with renal denervation durable to 30 months: SYMPLICITY HTN-2
2 COMMENTS - May 17, 2013 17:45 EDT
New data from the Symplicity HTN-2 study confirm the long-term efficacy of renal denervation in patients with resistant hypertension. At 30 months, there was a sustained reduction in systolic blood pressure, but researchers say this is only the beginning in terms of understanding the potential of the procedure.
Lipid/Metabolic
Dietary saturated fat has undeserved bad reputation, says review
3 COMMENTS - May 17, 2013 16:45 EDT
It calls for a reappraisal of health recommendations that focus on cutting saturated-fat intake levels, as "mechanisms for adverse health effects are lacking."
Hypertension
Physician inertia to blame for small BP changes in BARBER-1
May 17, 2013 11:45 EDT
A new analysis of BARBER-1 suggests that physician inertia might be the reason African-American men failed to reduce their blood pressure lower than hoped.
Prevention
Never too old to get moving: Aerobic fitness lowers risk of death in elderly
1 COMMENT - May 17, 2013 10:30 EDT
If you don't use it, you're going to lose it—the old chestnut is supported by a new VA Medical Center study showing that fit elderly patients with hypertension had a lower risk of death than those with low levels of cardiorespiratory fitness.
Thrombosis
EMA: Benefits outweigh VTE risks with hormone drugs for acne
May 17, 2013 09:30 EDT
The EMA has issued a recommendation that the benefits of the hormonal acne treatment Diane and its generics outweigh the risks, provided that several measures are taken to minimize the risk of thromboembolism.
Arrhythmia/EP
HRS members support charitable ICD/pacemaker donation for reuse overseas
May 16, 2013 17:30 EDT
A survey of the society's physician members shows there is wide support for, although also some concerns about, the practice, which remains controversial in the US.
Murmurs
Ken Mahaffey leaves DCRI for Stanford
May 16, 2013 16:15 EDT
Mahaffey is the second Duke physician to head to Stanford in the past two years, following in the footsteps of Dr Robert Harrington.
How low should you go? Experts debate latest salvo in the war on sodium
Prevention
How low should you go? Experts debate latest salvo in the war on sodium
6 COMMENTS - May 16, 2013 09:30 EDT
Earlier this week, the Institute of Medicine stirred up controversy when it stated the data are insufficient to recommend lowering sodium levels beyond 2300 mg per day. The AHA came out against the IOM report, but hypertension experts heartwire spoke with say the recommendations are right on the money.
Arrhythmia/EP
Dabigatran "real-life" results suggest caution needed
3 COMMENTS - May 15, 2013 17:15 EDT
New data from real-life experience of dabigatran for stroke prevention in AF shows that it is often used outside prescribing recommendations, and the risk of both thromboembolism and bleeding may be raised in patients switched from warfarin.
Arrhythmia/EP
No clinical gain, more risk: Preference for dual- vs single-chamber ICD again questioned
May 15, 2013 16:15 EDT
Applying only to primary-prevention patients with no pacing indications, an analysis suggests that more expensive dual-chamber implantable defibrillators, compared with single-chamber devices, pose a higher complication risk without any clinical advantage; yet they seem to be the ICD of choice for such patients, at least in the US.
IOM: No clear benefits to slashing sodium intake to 1500 mg/day
Prevention
IOM: No clear benefits to slashing sodium intake to 1500 mg/day
5 COMMENTS - May 15, 2013 11:40 EDT
Citing a lack of evidence linking lower sodium targets to a reduction in hard events, the IOM concludes that while Americans are consuming more sodium than required for health, the low limits set for certain high-risk groups are not supported by current evidence. The AHA respectfully disagrees.
Interventional/Surgery
Gene-mutation discovery in congenital heart disease spells major shift in care
May 15, 2013 09:15 EDT
The finding will fundamentally alter how congenital cardiac defects are categorized and potentially treated, say the authors of a new report.
Prevention
Rover Rx? Pet ownership may lower CVD risk, says AHA
May 14, 2013 16:00 EDT
The data suggest that owning a dog increases physical activity, but there are also good data on pets decreasing mental stress and decreasing blood pressure, according to the American Heart Association.
Lipid/Metabolic
Hormone therapy associated with MI in male-to-female transsexuals
3 COMMENTS - May 14, 2013 14:00 EDT
Hormone therapy given to transsexuals during gender reassignment appears to be associated with a greater likelihood of cardiovascular disease in men who subsequently become women.
Murmurs
Dr Allen Anderson joins Northwestern's Bluhm Cardiovascular Institute
May 14, 2013 13:45 EDT
Dr Allen Anderson is the new medical director of the advanced heart-failure program and director of network development at the Bluhm Cardiovascular Institute at Northwestern University.
Arrhythmia/EP
How close am I? Shocks decline when ICD programmers reminded of evidence-based settings
May 14, 2013 10:45 EDT
When they saw reports documenting shortfalls in their programming of ICDs to guidelines, clinicians cleaned up their act and shock rates safely fell; but this kind of teaching might not accomplish enough, researchers say.
Sodium levels through the restaurant roof—no reductions in past six years
Prevention
Sodium levels through the restaurant roof—no reductions in past six years
2 COMMENTS - May 13, 2013 16:30 EDT
A new study published today showed that while the sodium content of processed foods declined from 2005 to 2011, the overall reduction was just 3.5%. Restaurants, on the other hand, fared even worse, with researchers reporting that sodium levels actually increased by 2.6% over the same six-year period.
Arrhythmia/EP
Repeat ablation wins out over antiarrhythmic agents for recurrent paroxysmal AF
May 13, 2013 15:45 EDT
Not only was reablation more likely to banish recurrences in a randomized study, trying drugs the second time just made it worse for some patients.
Lipid/Metabolic
Simple tool stratifies mortality risk in type 2 diabetes
May 13, 2013 14:15 EDT
By plugging values for nine common variables into an online calculator, physicians can determine whether a patient with type 2 diabetes is at high risk of all-cause 2-year mortality, researchers report.
Brain/Kidney/Peripheral
Heparins not recommended in acute stroke
May 13, 2013 12:30 EDT
Analyzing individual patient data from the five largest trials of heparin in acute stroke has not been able to define a group of patients where the benefit outweighs the bleeding risk.
Interventional/Surgery
Risk factors help indicate which patients may be spared angiography
May 13, 2013 11:45 EDT
Cardiac-surgery patients without angina, MI, or diabetes show reduced risk of CAD and may be spared cost and comorbidities of conventional coronary angiography.
Interventional/Surgery
Early experience with valve-in-valve implantation shows positive outcomes
May 10, 2013 16:45 EDT
Results from use of the transcatheter valve-in-valve implantation in Nordic countries show few complications and low mortality rates.
Interventional/Surgery
Sliding-scale hydration reduces six-month clinical events in PCI patients
1 COMMENT - May 10, 2013 15:15 EDT
Hydration guided by left ventricular end-diastolic pressure significantly reduced the composite end point of death, MI, and the need for dialysis by 68% compared with a conventional hydration strategy.
Arrhythmia/EP
Few failures show up in Durata, Riata ST Optim defibrillator-lead analysis
1 COMMENT - May 10, 2013 14:30 EDT
It has limitations, but an analysis of St Jude registries suggests the Optim-insulated leads won't suffer the same issues that plagued the company's recalled Riata and Riata ST leads.
Long-term PROTECT-AF analysis: Watchman attains efficacy superiority over warfarin in AF
Thrombosis
Long-term PROTECT-AF analysis: Watchman attains efficacy superiority over warfarin in AF
May 10, 2013 10:00 EDT
The Watchman left-atrial appendage occluder had previously been found noninferior to warfarin in patients with nonvalvular atrial fibrillation; now, with an average of 45 months of follow-up, it's not only noninferior, it's superior, by some statistical measures.

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